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Fluorescent Probes, Labels, Particles and Stains > Fluorescent Enzyme Substrates > Alphabetical
Enzyme Substrates > Substrates by Enzyme > Aminopeptidase B
Biochemicals and Reagents > Fluorescent Probes, Labels, Particles and Stains > Detection
Fluorescent Probes, Labels, Particles and Stains > Fluorescent Enzyme Substrates > Fluorescent Enzyme Substrates for Spectroscopy
Enzyme Substrates > Substrates by Enzyme > Leucine Aminopeptidase

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W530179 (Aldrich)

WH0000142M1 (Sigma)

61888

Fluka

L-Leucine 7-amido-4-methyl coumarin hydrochloride

BioChemika, for fluorescence, ≥99.0% (HPLC)


Synonym:	L-Leucine-4-methyl-7-coumarinylamide hydrochloride, L-Leucine-4-methylumbelliferylamide hydrochloride, Leu-AMC
CAS Number:	62480-44-8
Linear Formula:	C₁₆H₂₀N₂O₃ · HCl
Molecular Weight:	324.80
Beilstein Registry Number:	1258699
MDL number:	MFCD00043262
PubChem Substance ID:	24882177

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Description

Other Notes

Fluorogenic substrate for leucine aminopeptidase¹

Properties

grade	for fluorescence
product line	BioChemika
assay	≥99.0% (HPLC)
optical activity	[α]20/D +62.0±2.0°, c = 1% in methanol
fluorescence	λ_ex 325 nm; λ_em 397 nm in 0.1 M Tris pH 8.0
	λ_ex 380 nm; λ_em 440 nm (after digestion with leucine aminopeptidase)
storage temp.	2-8°C

Safety

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements	22-24/25
WGK Germany	3

References

Cited Reference

1. Y. Kanaoka et al. Chem. Pharm. Bull. 25, 362, (1977) Abstract

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